This report shows that companies with science-based targets are delivering on large-scale emissions reductions. Five years on from the Paris Agreement, the Science Based Targets initiative (SBTi) analysed the emissions of a group of 338 companies whose climate targets have been approved by the SBTi as aligned with climate science and the goals of the Paris Agreement. This is the first ever study to look at how setting science-based targets correlates with corporate emissions reductions and the extent to which companies are actually delivering on those targets. Target-setting companies have successfully reduced their emissions by 25% since 2015, a difference of 302 million tonnes of CO2 equivalent, the same as the annual emissions from 78 coal-fired power plants.